Which condition denotes that the weapon is safest and should be handled with care?

Condition 4 denotes that the weapon is safest and should be handled with care because, in this condition, the firearm is unloaded, the chamber is clear, the magazine is removed, and the safety is engaged. This state significantly minimizes the risk of accidental discharge, making it the safest condition for handling the weapon. This scenario is crucial for ensuring that all personnel handling the weapon can do so without the immediate threat of it firing unintentionally.

All other conditions describe scenarios where the weapon may still contain ammunition or be in a ready-to-fire state, which necessitates a higher level of caution and care to prevent accidental discharge. Therefore, Condition 4 is emphasized during training as the safest method of handling and storing the firearm.